CLINICALLY USEFUL CALCITONIN ASSAYS

被引：7

作者：

CARTER, WB ^{[1
]}

HEATH, H ^{[1
]}

机构：

[1] MAYO CLIN & MAYO FDN,DIV ENDOCRINOL METAB & INTERNAL MED,ENDOCRINE RES UNIT,ROCHESTER,MN 55905

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1990年 / 1卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/1043-2760(90)90065-B

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Calcitonin assays are essential tools for research into calcitonin (CT) and C-cell physiology and pathophysiology. Several existing radio immunoassays for CT, based on polyclonal antisera, are generally reliable for detection and follow-up of patients having medullary thyroid carcinoma. Occasionally, however, these assays suffer from problems of specificity and sensitivity. Two-site immunometric techniques for CT offer potential for great improvement in sensitivity, specificity, and turnaround time over those based on classical competitive-binding radioimmunoassays. © 1990.

引用

页码：288 / 291

页数：4

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