ANTI-MULLERIAN HORMONE AND INTERSEX STATES

被引：45

作者：

JOSSO, N ^{[1
]}

BOUSSIN, L ^{[1
]}

KNEBELMANN, B ^{[1
]}

NIHOULFEKETE, C ^{[1
]}

PICARD, JY ^{[1
]}

机构：

[1] HOSP SICK CHILDREN, DEPT PEDIAT SURG, F-75743 PARIS 15, FRANCE

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1991年 / 2卷 / 06期

关键词：

D O I：

10.1016/1043-2760(91)90029-M

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Anti-Mullerian hormone (AMH), alias Mullerian-inhibiting substance or factor, plays a key role in fetal sex differentiation. The cloning of the human gene, a member of the transforming growth-factor-beta family and the development of immunochemical reagents recognizing circulating human AMH have opened new perspectives for clinical research. AMH assays and genetic studies now provide meaningful information regarding testicular function in infancy and the molecular basis of a rare form of male pseudohermaphroditism, the persistent Mullerian duct syndrome.

引用

页码：227 / 233

页数：7

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