Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein

被引：85

作者：

Hollingsworth, Robert E., Jr. ^{[1
]}

Chen, Phang-Lang ^{[1
]}

Lee, Wen-Hwa ^{[1
]}

机构：

[1] Univ Texas Hlth Sci Ctr San Antonio, Inst Biotechnol, Ctr Mol Med, San Antonio, TX 78245 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1993年 / 5卷 / 02期

基金：

美国国家卫生研究院;

关键词：

CDK-cyclin-dependent kinase; Rb-retinoblastoma protein; RCE-Rb control element;

D O I：

10.1016/0955-0674(93)90102-V

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Rapid progress in several areas of molecular biology has led to the realization that the retinoblastoma protein may play a pivotal role in the coordination between cell cycle control and regulation of gene expression. This role is a subtle one, and is important in only certain mammalian cell types. Exploring the details of these connections, and why only some cells rely on them, is already beginning to shed light on the regulation of cell multiplication.

引用

页码：194 / 200

页数：7

共 65 条

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