GENOMIC STRUCTURE OF THE PUTATIVE BTF3 TRANSCRIPTION FACTOR

被引：34

作者：

KANNO, M ^{[1
]}

CHALUT, C ^{[1
]}

EGLY, JM ^{[1
]}

机构：

[1] FAC MED STRASBOURG,CNRS,GENET MOLEC EUCARYOTES LAB,INSERM,U184,F-67085 STRASBOURG,FRANCE

来源：

GENE | 1992年 / 117卷 / 02期

关键词：

INTRON EXON; PROMOTER; HELA CELLS; INTERNAL DONOR SITE; TRANSCRIPTION FACTOR; GENE FAMILY; PHAGE-LAMBDA VECTORS;

D O I：

10.1016/0378-1119(92)90732-5

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

On the basis of the amino acid (aa) sequence of the putative BTF3 transcription factor, two complementary DNAs coding for the two proteins, BTF3a and BTF3b, have been cloned from a HeLa cell cDNA library. The two proteins are identical, except that BTF3b lacks the first 44 N-terminal aa present in BTF3a. These proteins originate from the same gene, which contains seven exons, and are the products of alternative splicing. The promoter region, containing a putative TATA box(es) and a CAAT box sequence, was identified. In addition, three other BTF3-like genes were characterized.

引用

页码：219 / 228

页数：10

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