THE UNIQUE PROPERTIES OF GLUTAMATE-RECEPTOR CHANNELS

被引：22

作者：

SPRENGEL, R

SEEBURG, PH

机构：

[1] Laboratory of Molecular Neuroscience, Center for Molecular Biology (ZMBH), Heidelberg University, D-6900 Heidelberg

来源：

FEBS LETTERS | 1993年 / 325卷 / 1-2期

关键词：

CHANNEL DETERMINANT; CA2+ PERMEABILITY; RNA EDITING;

D O I：

10.1016/0014-5793(93)81420-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Rapid excitatory neurotransmission in the central nervous system (CNS) is mediated predominantly by synaptically released L-glutamate which activates cation selective channels with different kinetic and ion conductance properties. Studies with cloned glutamate receptor channels helped delineate the functional properties of channels defined in subunit composition. Moreover, molecular studies have revealed novel genetic mechanisms controlling the expression of important structural channel determinants.

引用

页码：90 / 94

页数：5

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