MECHANISM OF EOSINOPHILIA AND MAST CELL DISRUPTION IN RATS INFESTED WITH PARASITE AMPLICAECUM ROBERTSI

被引：5

作者：

ARCHER, GT

机构：

[1] New South Wales Red Cross Blood Transfusion Service, Sydney

来源：

PATHOLOGY | 1969年 / 1卷 / 02期

关键词：

D O I：

10.3109/00313026909061047

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Rats infested with the ascaridoid parasite Amplicaecum robertsi were found to develop precipitating antibody to worm antigen as early as 24 hours after injection of the parasite. Experiments in vitro showed that the antigen-antibody precipitate was chemotactic to eosinophils. Phagocytosis by eosinophils of the antigen-antibody precipitate occurred and was followed by lysis of the eosinophil granules with discharge of granular material outside the cell. It appears that early antibody production may be responsible for the eosino-philia known to occur in rats infested with Amplicaecum. Mast cell changes were found to follow the local eosinophilia and to occur at sites of eosinophil accumulation. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：133 / &

共 16 条

[1] MOTION PICTURE STUDIES ON DEGRANULATION OF HORSE EOSINOPHILS DURING PHAGOCYTOSIS [J].