LAMINAR ANALYSIS OF BICUCULLINE-INDUCED EPILEPTIFORM ACTIVITY IN AREA-17 OF THE AWAKE MACAQUE

被引：44

作者：

SCHROEDER, CE ^{[1
]}

TENKE, CE ^{[1
]}

GIVRE, SJ ^{[1
]}

AREZZO, JC ^{[1
]}

VAUGHAN, HG ^{[1
]}

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT NEUROL,BRONX,NY 10461

来源：

BRAIN RESEARCH | 1990年 / 515卷 / 1-2期

关键词：

Alert macaque; Bicuculline; Current source density; Epilepsy; Multiunit activity; Striate cortex; Visual evoked potential;

D O I：

10.1016/0006-8993(90)90617-K

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We investigated the laminar profile of visually evoked paroxysmal discharge following bicuculline administration in area 17 of the alert macaque. Paroxysmal discharge was focussed in lamina 3, with lesser concomitants in infragranular laminae. There were no marked effects on the flash-evoked laminar activation sequence. The neocortex of the alert macaque studied with the present techniques may provide a model for evaluating basic mechanisms of epilepsy, and for linking these to the macroscopic phenomena seen in humans. © 1990.

引用

页码：326 / 330

页数：5

共 12 条

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