ALTERED RESPONSE TO APOMORPHINE AND HALOPERIDOL AFTER 9 DAYS OF COCAINE INJECTIONS

被引：7

作者：

EPSTEIN, PN ^{[1
]}

ALTSHULER, HL ^{[1
]}

机构：

[1] BAYLOR UNIV,COLL MED,TEXAS MED CTR,HOUSTON,TX 77030

来源：

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1979年 / 10卷 / 02期

关键词：

Apomorphine; Catalepsy; Cocaine; Haloperidol; Stereotype; Tolerance;

D O I：

10.1016/0091-3057(79)90085-6

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Sprague Dawley rats, pretreated with nine daily injections of 20 mg/Kg cocaine or saline, were evaluated for aspects of their behavioral response to apomorphine, haloperidol, or cocaine, twenty-four hours after their last pretreatment injection. Data obtained from saline and cocaine pretreated animals indicated that: cocaine pretreated rats were more sensitive to haloperidol-induced catalepsy, less responsive to some of the stereotypic effects of apomorphine and similar in their responses to the anticataleptic properties of cocaine. © 1979.

引用

页码：189 / 193

页数：5

共 22 条

[1]

ALTSHULER HL, 1976, COCAINE CHEM BIOL CL, P133

[2] TOLERANCE PHENOMENA WITH NEUROLEPTICS CATALEPSY, APOMORPHINE STEREOTYPES AND STRIATAL DOPAMINE METABOLISM IN RAT AFTER SINGLE AND REPEATED ADMINISTRATION OF LOXAPINE AND HALOPERIDOL [J].