SERUM CREATINE KINASE-BB LINKED TO IMMUNOGLOBULIN-G

被引：41

作者：

BOHNER, J ^{[1
]}

STEIN, W ^{[1
]}

KUHLMANN, E ^{[1
]}

EGGSTEIN, M ^{[1
]}

机构：

[1] MED KLIN TUBINGEN,INNERE MED ABT 4,D-7400 TUBINGEN 1,FED REP GER

来源：

CLINICA CHIMICA ACTA | 1979年 / 97卷 / 01期

关键词：

D O I：

10.1016/0009-8981(79)90027-5

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

We describe an atypical form of creatine kinase in the serum of a woman after myocardial infarction. Electrophoresis on agarose gel showed a single fraction between CK-MM and CK-MB isoenzymes. After ion-exchange chromatography on DEAE-Sephadex A-50 we isolated the atypical CK and CK-BB as detected by electrophoresis of the eluted fractions. Results of our immunological investigations and exclusion chromatography clearly demonstrate that the atypical CK consists of complexes with high molecular masses formed by CK-BB isoenzyme and immunoglobulin G. The clinical significance, if any, of this Macro CK has yet to be determined. © 1979.

引用

页码：83 / 88

页数：6

共 16 条

[1]

DAWSON DM, 1967, J BIOL CHEM, V242, P210

[2] CREATINE-KINASE B-SUBUNIT ACTIVITY IN HUMAN-SERUM .1. DEVELOPMENT OF AN IMMUNOINHIBITION METHOD FOR ROUTINE DETERMINATION OF S-CREATINE KINASE B-SUBUNIT ACTIVITY [J].

GERHARDT, W ;

LJUNGDAHL, L ;

BORJESSON, J ;

HOFVENDAHL, S ;

HEDENAS, B .

CLINICA CHIMICA ACTA, 1977, 78 (01) :29-41

[3]

GORMAN WW, 1976, CLIN CHEM, V22, P1539

[4] CREATINE-KINASE ISOENZYME BB IN SERUM OF HEALTHY ADULTS AND CHILDREN [J].

JUNG, K ;

NEUMANN, R ;

COBET, G ;

NUGEL, E ;

EGGER, E .

CLINICA CHIMICA ACTA, 1979, 91 (02) :165-168

[5] CREATINE-KINASE ISOENZYMES - IDIOPATHIC OCCURRENCE OF CREATINE-KINASE BB ACTIVITIES IN PATIENT SERUM [J].

LANG, H ;

WURZBURG, U ;

NEUMEIER, D ;

KNEDEL, M ;

PRELLWITZ, W ;

KATTERMANN, R ;

SCHLEBUSCH, H ;

SCHURMANN, J .

KLINISCHE WOCHENSCHRIFT, 1978, 56 (13) :641-646

[6]

MORIN LG, 1977, CLIN CHEM, V23, P646

[7]

NEALON DA, 1979, CLIN CHEM, V25, P332

[8]

PRABHAKARAN V, 1979, CLIN CHEM, V25, P112

[9]

SAX SM, 1976, CLIN CHEM, V22, P87

[10]

SIEG JF, 1977, DTSCH MED WOCHENSCHR, V45, P1647

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