ANALYZING ISOENZYME BAND PATTERNS USING SIMILARITY COEFFICIENTS - A PERSONAL-COMPUTER PROGRAM

被引：14

作者：

STEVENS, JR ^{[1
]}

CIBULSKIS, RE ^{[1
]}

机构：

[1] UNIV LIVERPOOL,LIVERPOOL SCH TROP MED,DEPT INT COMMUNITY HLTH,LIVERPOOL L3 5QA,ENGLAND

来源：

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE | 1990年 / 33卷 / 04期

基金：

英国医学研究理事会;

关键词：

SIMILARITY COEFFICIENT; ISOENZYME; TRYPANOSOMIASIS;

D O I：

10.1016/0169-2607(90)90071-G

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

A computer program in Fortran 77 was developed to analyse the isoenzyme patterns of trypanosomes isolated from African sleeping sickness patients, to allow biochemical relationships between populations of trypanosomes from different hosts and geographic areas to be elucidated. However, the generality of the design allows it to be used with presence/absence data from a variety of sources, including DNA fingerprints. The program reads in isoenzyme band patterns from an ASCII file and calculates a matrix of similarity coefficients. Four different similarity measures are offered, suitable for presence/absence data from a range or organisms and experimental procedures. The matrix of similarity values produced is suitable for analysis by ordination methods including principal coordinates analysis, and the production of dendrograms and icicle plots using SPSS/PC+.

引用

页码：205 / 212

页数：8

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