ANTIDOPAMINERGIC ACTIVITY OF ESTROGENS ON PROLACTIN-RELEASE AT THE PITUITARY LEVEL INVIVO

被引:36
作者
FERLAND, L [1 ]
LABRIE, F [1 ]
EUVRARD, C [1 ]
RAYNAUD, JP [1 ]
机构
[1] CTR RECH ROUSSEL UCLAF, F-93230 ROMAINVILLE, FRANCE
关键词
antidopaminergic; estrogens; pituitary; prolactin;
D O I
10.1016/0303-7207(79)90045-5
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Treatment of female or male rats with estradiol benzoate led to an almost complete reversal of the inhibitory effect of low doses of dopamine on prolactin secretion. These data indicate that estrogens which have previously been shown to exert a potent antidopaminergic activity on prolactin secretion in anterior pituitary cells in primary culture have similar effects in vivo. © 1979.
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页码:199 / 204
页数:6
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