IMMUNE-COMPLEX INVOLVEMENT IN THE PATHOGENESIS OF INFECTIOUS BURSAL DISEASE VIRUS IN CHICKENS

被引：17

作者：

LEY, DH ^{[1
]}

YAMAMOTO, R ^{[1
]}

BICKFORD, AA ^{[1
]}

机构：

[1] UNIV CALIF DAVIS,VET EXTENS,DAVIS,CA 95616

来源：

AVIAN DISEASES | 1979年 / 23卷 / 01期

关键词：

D O I：

10.2307/1589689

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Frozen kidney sections from chickens inoculated with infectious bursal disease virus (IBDV) were stained with fluorescein-conjugated rabbit anti-chicken gamma-globulin. Fluorescence was observed in the renal glomeruli of infected chickens, indicating that gamma-globulins, probably in the form of immune complexes, had lodged in the glomeruli of IBDV-infected chickens. This suggests that immune complexes may play an important role in the pathogenesis of IBDV infections in chickens.

引用

页码：219 / 224

页数：6