CONFORMATION AND MOLECULAR-BIOLOGY OF POLYPEPTIDE HORMONES .2. GLUCAGON

被引：11

作者：

BLUNDELL, T

机构：

[1] Tom Blundell is at the Laboratory of Molecular Biology, Department of Crystallography, Birkbeck College, London WCIE 7HX, Malet Street

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1979年 / 4卷 / 04期

关键词：

D O I：

10.1016/0968-0004(79)90187-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Monomeric glucagon has an extended flexible structure. Self-association to trimers and higher oligomers is accompanied by the formation of helix. It is probable that a helical conformer is also stabilized when glucagon binds its membrane receptor. © 1979.

引用

页码：80 / 83

页数：4

共 25 条

[1] FORMATION AND STRUCTURE OF GELS AND FIBRILS FROM GLUCAGON
BEAVEN, GH
GRATZER, WB
DAVIES, HG
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1969, 11 (01): : 37 - &
[2] BIOCHEMISTRY OF THE PROTEIN HORMONES
BEHRENS, OK
BROMER, WW
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1958, 27 : 57 - 100
[3] EVIDENCE OF ASSOCIATION OF GLUCAGON FROM OPTICAL ROTATORY DISPERSION AND CONCENTRATION-DIFFERENCE SPECTRA
BLANCHARD, MH
KING, MV
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1966, 25 (03) : 298 - +
[4] RELATION OF STRUCTURE TO STORAGE AND RECEPTOR-BINDING OF GLUCAGON
BLUNDELL, TL
DOCKERILL, S
SASAKI, K
TICKLE, IJ
WOOD, SP
[J]. METABOLISM-CLINICAL AND EXPERIMENTAL, 1976, 25 (11): : 1331 - 1339
[5] HISTOCHEMICAL AND ULTRASTRUCTURAL STUDIES ON PANCREATIC A-CELLS - EVIDENCE FOR GLUCAGON AND NON-GLUCAGON COMPONENTS OF ALPHA GRANULE
BUSSOLATI, G
CAPELLA, C
VASSALLO, G
SOLCIA, E
[J]. DIABETOLOGIA, 1971, 7 (03) : 181 - +
[6] CONFORMATION OF GLUCAGON - PREDICTIONS AND CONSEQUENCES
CHOU, PY
FASMAN, GD
[J]. BIOCHEMISTRY, 1975, 14 (11) : 2536 - 2541
[7] STUDY OF CONFORMATIONAL PROPERTIES OF GLUCAGON IN PRESENCE OF GLYCOLS
CONTAXIS, CC
EPAND, RM
[J]. CANADIAN JOURNAL OF BIOCHEMISTRY, 1974, 52 (06): : 456 - 468
[8] EDELHOCH H, 1969, J BIOL CHEM, V244, P3876
[9] INTERACTION OF GLUCAGON WITH DIMYRISTOYL GLYCEROPHOSPHOCHOLINE
EPAND, RM
JONES, AJS
SCHREIER, S
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1977, 491 (01) : 296 - 304
[10] THERMODYNAMICS OF SELF-ASSOCIATION OF GLUCAGON
FORMISANO, S
JOHNSON, ML
EDELHOCH, H
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (08) : 3340 - 3344

← 1 2 3 →