OPIOID-BINDING CELL-ADHESION MOLECULE (OBCAM)-RELATED CLONES FROM A RAT-BRAIN CDNA LIBRARY

被引：24

作者：

LIPPMAN, DA

LEE, NM

LOH, HH

机构：

[1] Department of Pharmacology, University of Minnesota Medical School, Minneapolis

来源：

GENE | 1992年 / 117卷 / 02期

关键词：

OPIOID RECEPTOR; CELL ADHESION MOLECULES; CDNA CLONING; IMMUNOGLOBULIN SUPERFAMILY;

D O I：

10.1016/0378-1119(92)90734-7

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A rat brain cDNA library was screened with probes constructed from portions of the cDNA (OBCAM) encoding the opioid-binding cell adhesion molecule (OBCAM). Three clones of interest were isolated and sequenced. The largest clone, DUZ1, had a putative open reading frame (ORF) essentially identical to OBCAM in its C-terminal 318 amino acids (aa), but differing in its N-terminal aa (20 vs. 27 in OBCAM), and in all of its 5'-noncoding regions. The other clones, SG8 and SG13, had a putative ORF essentially identical to that of OBCAM, but differed from each other in a portion of their 5'-noncoding region. This study suggests that there is a family of OBCAM-like genes.

引用

页码：249 / 254

页数：6

共 16 条

[1]

ANN DK, 1992, J BIOL CHEM, V262, P7921

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