CHROMOSOMAL-ANOMALIES CAUSED BY PREOVULATORY OVER-RIPENESS OF THE PRIMARY OOCYTE

被引：10

作者：

KAMIGUCHI, Y

FUNAKI, K

MIKAMO, K

机构：

[1] Department of Biological Sciences, Asahikawa Medical College, Asahikawa

来源：

PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES | 1979年 / 55卷 / 08期

关键词：

D O I：

10.2183/pjab.55.398

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Effects of preovulatory overripeness of primary oocytes were studied cytogenetically in 2-cell rat embryos which developed from the ova unduely aged for 48 hours in mature follicles. Both aneuploids and mosaics increased significantly in the experimental group. It was clearly indicated that the delayed ovulation induces nondis j unction and anaphase lag of chromosomes during both the meiotic and first cleavage divisions. A significant increase of polyploidy was also proven as the result of the delay in ovulation. Its causal mechanism was confirmed to be polyspermy. © 1979, The Japan Academy. All rights reserved.

引用

页码：398 / 402

页数：5

共 9 条

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