STEREOSELECTIVE PREPARATION OF INDOLOQUINOLIZIDINE N-OXIDES - PREDOMINANT CONFORMATIONS

被引：17

作者：

LOUNASMAA, M

TAMMINEN, T

机构：

[1] Laboratory for Organic and Bioorganic Chemistry, Technical University of Helsinki

来源：

TETRAHEDRON | 1991年 / 47卷 / 16-17期

关键词：

D O I：

10.1016/S0040-4020(01)87093-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Stereoselective preparation of indoloquinolizidine N-oxides possessing the N(b)-oxygen - C(12b) -hydrogen relationship, trans or cis at will, is described. Contribution of the different conformations to the conformational equilibrium is studied by C-13 NMR spectroscopy, and significance of the N(b)-oxygen - C(12b)-hydrogen relationship for the regioselective transformation of indoloquinolizidine N-oxides to the corresponding iminium ions is discussed.

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页码：2879 / 2894

页数：16

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