CHARACTERIZATION OF PYROLYSIS CONDITIONS AND INTERFERENCE BY OTHER COMPOUNDS IN THE CHEMI-LUMINESCENCE DETECTION OF NITROSAMINES

Facile analysis of N-nitroso compounds has been made possible by the development of chemiluminescence detectors. Response of one such detector as a function of pyrolysis chamber temperature has been characterized for several nitrosamines and for an aliphatic C-nitro compound, an aromatic C-nitro compound, a nitramine, an alkylnitrite, and a nitrosourea. The response-temperature profiles are valuable in distinguishing among the various compounds and in optimizing the sensitivity of the detector for use in chromatography. Other tests, including photolysis and stability toward nitrite-scavenging reagents, further aid in distinguishing among the various compounds. © 1979, American Chemical Society. All rights reserved.