SPATIAL CONTROL OF THE GAP GENE KNIRPS IN THE DROSOPHILA EMBRYO BY POSTERIOR MORPHOGEN SYSTEM

被引：70

作者：

PANKRATZ, MJ ^{[1
]}

BUSCH, M ^{[1
]}

HOCH, M ^{[1
]}

SEIFERT, E ^{[1
]}

JACKLE, H ^{[1
]}

机构：

[1] INST GENET & MIKROBIOL, W-8000 MUNICH 19, GERMANY

来源：

SCIENCE | 1992年 / 255卷 / 5047期

关键词：

D O I：

10.1126/science.1546296

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The gap genes of Drosophila are the first zygotic genes to respond to the maternal positional signals and establish the body pattern along the anterior-posterior axis. The gap gene knirps, required for patterning in the posterior region of the embryo, can be activated throughout the wild-type embryo and is normally repressed from the anterior and posterior sides. These results provide direct molecular evidence that the posterior morphogen system interacts in a fundamentally different manner than do hunchback and bicoid, which are responsible for anterior pattern formation.

引用

页码：986 / 989

页数：4

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