STEREOSELECTIVE CONSTRUCTION OF FUNCTIONALIZED BICYCLIC CARBOCYCLES THROUGH METAL-HALOGEN EXCHANGE-INITIATED SEQUENTIAL CONJUGATE ADDITION-REACTIONS

被引：15

作者：

COOKE, MP

GOPAL, D

机构：

[1] Department of Chemistry, Washington State University, Pullman

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 18期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0040-4039(00)76638-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Rapid metal-halogen exchange reactions have been used to initiate the stereoselective formation of trans-bicyclo[4.3.0]nonane and strained trans-bicyclo[3.3.0]octane derivatives through sequential intramolecular conjugate addition reactions. Stereoselectivity has been controlled in anionic olefin addition reactions as well as in corresponding radical cyclizations through control of acceptor olefin stereochemistry.

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收藏

页码：2837 / 2840

页数：4

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