LOCAL ADJUVANTS - INFLUENCE OF SODIUM DODECYLBENZENE SULFONATE ON IMMUNIZATION WITH AEROSOLIZED ANTIGEN

被引：8

作者：

MARKHAM, RJF

WILKIE, BN

机构：

[1] Department of Veterinary Microbiology and Immunology, University of Guelph, Guelph, Ontario

来源：

EXPERIENTIA | 1979年 / 35卷 / 03期

关键词：

D O I：

10.1007/BF01964385

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Guinea-pig respiratory and serum antibody responses were enhanced following exposure to aerosols of bovine IgG2 dissolved in solutions of sodium dodecylbenzene sulphate (SDBS). Enhanced response was seen in both primary and secondary immunization. Cell-mediated immune response (indirect macrophage migration influencing test) was not altered by SDBS. Results are discussed with a view to the possible utility of SDBS as adjuvant for prophylactic immunization. © 1978 Birkhäuser Verlag.

引用

页码：414 / 416

页数：3

共 16 条

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