VITAMIN-K-DEPENDENT CARBOXYLASE - INFLUENCE OF THE PROPEPTIDE REGION ON ENZYME-ACTIVITY

被引：32

作者：

CHEUNG, A ^{[1
]}

ENGELKE, JA ^{[1
]}

SANDERS, C ^{[1
]}

SUTTIE, JW ^{[1
]}

机构：

[1] UNIV WISCONSIN,COLL AGR & LIFE SCI,DEPT BIOCHEM,MADISON,WI 53706

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1989年 / 274卷 / 02期

关键词：

D O I：

10.1016/0003-9861(89)90472-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：574 / 581

页数：8

共 29 条

[1]

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[2]

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[3]

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[4] MOLECULAR-BASIS OF HEMOPHILIA-B - A DEFECTIVE ENZYME DUE TO AN UNPROCESSED PROPEPTIDE IS CAUSED BY A POINT MUTATION IN THE FACTOR-IX PRECURSOR [J].

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FURIE, B .

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[5] THE EARLY STAGES IN THE BIOSYNTHESIS OF PROTHROMBIN [J].

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ESNOUF, MP .

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[6] PROPEPTIDE OF HUMAN PROTEIN-C IS NECESSARY FOR GAMMA-CARBOXYLATION [J].

FOSTER, DC ;

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HAGEN, FS ;

SPRECHER, CA ;

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DAVIE, EW .

BIOCHEMISTRY, 1987, 26 (22) :7003-7011

[7] THE MOLECULAR-BASIS OF BLOOD-COAGULATION [J].

FURIE, B ;

FURIE, BC .

CELL, 1988, 53 (04) :505-518

[8] RECOGNITION SITE DIRECTING VITAMIN-K-DEPENDENT GAMMA-CARBOXYLATION RESIDES ON THE PROPEPTIDE OF FACTOR-IX [J].

JORGENSEN, MJ ;

CANTOR, AB ;

FURIE, BC ;

BROWN, CL ;

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FURIE, B .

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[9]

KNOBLOCH JE, 1987, J BIOL CHEM, V262, P15334

[10]

LARSON AE, 1981, J BIOL CHEM, V256, P1032

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