BINDING AND ELECTRON TRANSFER TO CYTOCHROME-C IN ARTIFICIAL PHOSPHOLIPID MEMBRANES

被引：27

作者：

KIMELBERG, HK

LEE, CP

机构：

[1] Johnson Research Foundation, School of Medicine University of Pennsylvania, Philadelphia

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 34卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0006-291X(69)90248-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The binding characteristics of cytochrome c to mixed cardiolipin lecithin membrane systems are described. This binding is reduced by increasing the ionic strength or by omitting cardiolipin. Only some 10 to 20% of the cytochrome c is reduced by ascorbate, and dithionite gives only a small further increase. The remaining cytochrome c is, however, rapidly reduced if TMPD or PMS is added. The relationship of these findings to work on mitochondrial systems is discussed, and an interpretation based on the permeability characteristics of the membrane is proposed. © 1969.

引用

页码：784 / +

页数：1

共 19 条

[1] PHOSPHOLIPASE-INDUCED RELEASE OF CYTOCHROME-C FROM THE ELECTRON TRANSPORT PARTICLE [J].