BONE-MARROW SCINTIGRAPHY IN PROSTATIC CARCINOMAS

被引：8

作者：

BOURGEOIS, P

MALARME, M

VANFRANCK, R

WAUTERS, G

FERREMANS, W

机构：

[1] C.H.J. Bracops, Department of Nuclear Medicine

[2] Service of Urology, Université Libre de Bruxelles, Brussels, 1070, 79, rue Dr Huet

来源：

NUCLEAR MEDICINE COMMUNICATIONS | 1991年 / 12卷 / 01期

关键词：

D O I：

10.1097/00006231-199101000-00005

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Bone marrow scintigrams (MS) were performed on 73 men with histologically proven prostatic carcinomas. Follow-up data were available in 24 cases. Thirty-six patients had skeletal metastases at the time of the first MS investigation. They were compared with conventional bone scintigrams (BS) as well as clinical, biological, radiological and other follow-up data obtained for the same patients. At the present stage of revision and of follow-up of our patients, MS appeared less sensitive than BS in diagnosing skeletal metastases (94% as against 100% if all abnormal MS and BS presentations are considered as diagnostic or 83% as against 86% if more restrictive analytic criteria were applied). On the other hand, MS showed slightly higher specificity (81% for MS as against 73% for BS) when all abnormal MS and BS presentations are considered as diagnostic. With more restrictive diagnostic criteria, BS remains more specific (100%) than MS (87%). Nevertheless, the likelihood of bone metastasis is low when a normal MS is found in case of dubious BS situations, but high when the MS is pathological. In 11 patients with skeletal metastasis for whom follow-up investigations were available, MS appeared better than (4 cases) or equivalent to (6 cases) BS for evaluating the responses and the ultimate evolution of the disease. Marrow scintigrams are thus a useful tool in cases of dubious BS and for evaluating the response of skeletal metastasis to treatment.

引用

页码：35 / 45

页数：11

共 16 条

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