ULTRASONIC CHARACTERISTICS OF THE UTERUS AND OVARIES IN RELATION TO PUBERTAL DEVELOPMENT AND SERUM LH, FSH, AND ESTRADIOL CONCENTRATIONS

被引：18

作者：

CACCIATORE, B

APTER, D

ALFTHAN, H

STENMAN, UH

机构：

来源：

ADOLESCENT AND PEDIATRIC GYNECOLOGY | 1991年 / 4卷 / 01期

关键词：

ULTRASOUND; OVARIAN VOLUME; UTERINE VOLUME; PUBERTAL DEVELOPMENT; IMMUNOFLUOROMETRIC ASSAY;

D O I：

10.1016/S0932-8610(12)80084-3

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Ultrasound was used to evaluate uterine and ovarian volume and morphology and these findings were related to serum concentrations of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), assessed by a highly sensitive immunofluorometric assay, and estradiol, assessed by radioimmunoassay (RIA). Fifty healthy premenarcheal schoolgirls, 15 postmenarcheal girls, and 15 adult women comprised the study groups. Uterine volume did not change, whereas ovarian volume slightly increased from 7 to 9 years. With the onset of puberty, at about 10 years of age, the uterus started to grow rapidly and ovarian volume increased further. The number of follicles greater-than-or-equal-to 5 mm in diameter increased significantly from 7 to 9 years of age. At 10-12.5 years, the ovaries were multifollicular in the majority of the girls. Uterine and ovarian volume and LH, FSH, and estradiol levels correlated with age and with each other (p < 0.001). Below 10 years of age, only ovarian volume and FSH concentrations correlated with age (p < 0.05) and with each other (p < 0.05). The increment in follicular growth detected by ultrasound was related to the prepubertal FSH levels and it may represent a sign anticipating the onset of puberty. Sonographic evaluation of the uterus and ovaries reflects functional changes and appears useful for assessment of gonadal development during puberty.

引用

页码：15 / 20

页数：6

共 18 条

[1]

Lippe BM, Sample F, Pelvic ultrasonography in pediatric and adolescent endocrine disorders, J Pediatr, 92, (1978)

[2]

Haller JO, Schneider M, Kassner G, Et al., Ultrasonography in pediatric gynecology and obstetrics, Am J Roentgenol, 128, (1977)

[3]

Orsini LF, Salardi S, Pilu G, Et al., Pelvic organs in premenarcheal girls: real time ultrasonography, Radiology, 153, (1984)

[4]

Ivarsson SA, Nilsson KO, Persson P-H, Ultrasonography of the pelvic organs in prepubertal and post-pubertal girls, Arch Dis Child, 58, (1983)

[5]

Stanhope R, Adams J, Jakobs HS, Et al., Ovarian ultrasound assessment in normal children, idiopathic precocious puberty and during low dose pulsatile gonadotropin releasing hormone treatment of hypo-gon-adotrophic hypogonadism, Arch Dis Child, 60, (1985)

[6]

Winer-Muram HT, Emerson DE, Muram D, Et al., The sonographic features of the peripubertal ovaries, Adolesc Pediatr Gynecol, 2, (1989)

[7]

Sanfilippo JS, Lavery JP, The spectrum of ultrasound: antenatal to adolescent years, Sem Repro Endocrinol, 6, (1988)

[8]

Stenman U-H, Alfthan H, Koskimies A, Et al., Monitoring the LH surge by ultrarapid and highly sensitive immunofluorometric assay, Ann NY Acad Sei, 442, (1985)

[9]

Apter D, Cacciatore B, Alfthan H, Et al., Serum LH concentrations increase 100-fold in females from 7 years of age to adulthood as measured by time-resolved immunofluorometric assay, J Clin Endocrinol Metab, 68, (1989)

[10]

Tanner JM, (1962)

← 1 2 →