PERCEPTION OF BRONCHOCONSTRICTION IN CHRONIC ASTHMA

被引:19
作者
BONER, AL
DESTEFANO, G
PIACENTINI, GL
BONIZZATO, C
SETTE, L
BANFI, F
HINDIALEXANDER, MC
机构
[1] Pediatric Department, University of Verona, Verona
[2] Istituto Pio XII Misurina, Belluno
[3] Glaxo Italy Biostatistics, Buffalo, NY
[4] University of Buffalo, Buffalo, NY
关键词
D O I
10.3109/02770909209044792
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Twenty-nine asthmatic children were studied to assess their ability to detect the severity of their bronchoconstriction. First (STEP 0): each child was asked if he "felt asthma," inviting him to give a self-estimated obstruction score (SEOS) from 0 (no asthma) to 3 (severe asthma) and a baseline FEV, was recorded. Then (STEP 1): methacholine was administered to all except 9 children with an FEV1 < 80% of predicted who received saline nebulization and a second SEOS was recorded. Finally: salbutamol aerosol was administered and a third SEOS and FEV1 were obtained (STEP 2). Spearman's correlation coefficients r between SEOS and FEV, were for the overall population -0.602, -0.517, and -0.104 at STEP 0, STEP 1, and STEP 2, respectively. The r values reduction during the trial can be due either to a decrease of children's concentration during the study or to a real difficulty in recognizing repeated changes in airway status. Some children tend to underestimate their bronchospasm. For these patients an accurate assessment of the severity of the bronchoconstriction requires an objective measurement during acute changes in asthmatic children.
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收藏
页码:323 / 330
页数:8
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