IMMUNOGLOBULIN SYNTHESIS IN NEONATAL NURSE SHARKS (GINGLYMOSTOMA CIRRATUM)

被引:38
作者
FIDLER, JE
CLEM, LW
SMALL, PA
机构
[1] Department of Microbiology, College of Medicine, University of Florida, Gainesville, FL
来源
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY | 1969年 / 31卷 / 02期
基金
美国国家卫生研究院;
关键词
19S IgM; 7S IgM; Ginglymostoma cirratum temporal synthesis of IgM; Immunoglobulin synthesis; neonatal proteins; neonatal sharks; nurse sharks; ontogeny; phylogeny; quantitative radial immunodiffusion; radial immunodiffusion; serum proteins; γM immunoglobulin;
D O I
10.1016/0010-406X(69)91660-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1. 1. Newborn nurse sharks were shown to have low levels of IgM at birth. 2. 2. The immunoglobulin present at birth was shown to be of the 19S form. The 7S form was found to appear later; both immunoglobulins increased in concentration throughout the first 42 days of life, at which time they were still less than half the adult levels. 3. 3. These observations support the hypothesis that shark 19S and 7S IgM are independently released into the circulation. © 1969.
引用
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页码:365 / &
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