VERRUCARINS AND RORIDINS .38. PARTIAL SYNTHESIS OF 3'-HYDROXY-2'-DEOXY-2',3'',4'',5''-TETRAHYDROVERRUCARIN-A

被引：14

作者：

NOTEGEN, EA ^{[1
]}

TORI, M ^{[1
]}

TAMM, C ^{[1
]}

机构：

[1] UNIV BASEL, INST ORGAN CHEM, CH-4056 BASEL, SWITZERLAND

来源：

HELVETICA CHIMICA ACTA | 1981年 / 64卷 / 01期

关键词：

D O I：

10.1002/hlca.19810640132

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The macrocyclic trichothecene triester 3''-hydroxy-2''-deoxy-2",3",4",5"-tetrahydroverrucarin A [a potential antineoplastic drug] was synthesized starting from the sesquiterpene alcohol verrucarol, adipic acid and a derivative of mevalonic acid. The latter was prepared from 4-(tetrahydro-2-pyranyloxy)-2-butanone.

引用

页码：316 / 328

页数：13

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