ACTIVATION OF BOVINE PLASMINOGEN BY STREPTOCOCCUS-UBERIS

被引：40

作者：

LEIGH, JA

机构：

[1] Institute for Animal Health, Compton Laboratory, Compton, Newbury

来源：

FEMS MICROBIOLOGY LETTERS | 1993年 / 114卷 / 01期

关键词：

PLASMINOGEN; STREPTOCOCCUS; MASTITIS; STREPTOKINASE;

D O I：

10.1111/j.1574-6968.1993.tb06552.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Culture filtrate from Streptococcus uberis was found to activate bovine and equine plasminogen but not that from rabbit, human or porcine plasma. In contrast, streptokinase from a Lancefield group C Streptococcus activated human plasminogen but not that from bovine, porcine and rabbit plasma. Very slight activity was observed against equine plasminogen. Plasmin was detected by hydrolysis of skimmed milk protein in agarose. The activation of bovine plasminogen by S. uberis culture filtrate resulted in the formation of three polypeptides with molecular masses of 56, 26 and 21 kDa. This is the first report of a streptokinase activity from this species.

引用

页码：67 / 71

页数：5

共 14 条

[1]

ASTON JW, 1975, AUST J DAIRY TECHNOL, V30, P55

[2] VARIATION WITH SEASON AND LACTATION OF PLASMIN AND PLASMINOGEN CONCENTRATIONS IN MONTBELIARD COWS MILK [J].