LETHAL EFFECT OF HETEROLOGOUS NUCLEI IN AMOEBA HETEROKARYONS

被引:29
作者
JEON, KW
LORCH, IJ
机构
[1] Cell Physiology Laboratory, Center for Theoretical Biology, State University of New York, Buffalo
基金
美国国家卫生研究院;
关键词
D O I
10.1016/0014-4827(69)90007-X
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The viability of heterokaryons obtained by nuclear transplantation between different strains of amoebae was studied. A heterokaryon gave rise to two kinds of cells, one containing the host and the other the heterologous nucleus. The latter were never viable, and more than 90 % of the host cells also failed to form clones when the heterologous nuclei were present 15 min or longer. The lethal action was apparently caused by a diffusible factor which acted primarily on the nuclei of the host cells. © 1969.
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页码:233 / &
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