EVIDENCE FOR LIDOCAINE-INDUCED ENZYME INACTIVATION

被引：30

作者：

SAVILLE, BA

GRAY, MR

TAM, YK

机构：

[1] UNIV ALBERTA,DEPT CHEM ENGN,EDMONTON T6G 2G6,ALBERTA,CANADA

[2] UNIV ALBERTA,FAC PHARM & PHARMACEUT SCI,EDMONTON T6G 2G6,ALBERTA,CANADA

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1989年 / 78卷 / 12期

关键词：

D O I：

10.1002/jps.2600781207

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1003 / 1008

页数：6

共 20 条

[1] SPECTRAL INTERACTION OF ORPHENADRINE AND ITS METABOLITES WITH OXIDIZED AND REDUCED HEPATIC-MICROSOMAL CYTOCHROME-P-450 IN THE RAT [J].

BAST, A ;

NOORDHOEK, J .

BIOCHEMICAL PHARMACOLOGY, 1982, 31 (17) :2745-2753

[2] INFLUENCE OF LONG-TERM INFUSIONS ON LIDOCAINE KINETICS [J].

BAUER, LA ;

BROWN, T ;

GIBALDI, M ;

HUDSON, L ;

NELSON, S ;

RAISYS, V ;

SHEA, JP .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1982, 31 (04) :433-437

[3]

BAX NDS, 1980, BRIT J CLIN PHARMACO, V10, P353

[4] LIDOCAINE UPTAKE IN ISOLATED RAT HEPATOCYTES AND EFFECTS OF DL-PROPRANOLOL [J].

CHEN, CP ;

VU, VT ;

COHEN, SD .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1980, 55 (01) :162-168

[5]

EGAN RW, 1976, J BIOL CHEM, V251, P7329

[6]

GRAY MR, 1987, DRUG METAB DISPOS, V15, P22

[7]

IVANETICH KM, 1980, BIOCHEM PHARMACOL, V29, P2808

[8] SIMULTANEOUS QUANTITATION OF LIDOCAINE AND ITS 4 METABOLITES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY - APPLICATION TO STUDIES ON INVITRO AND INVIVO METABOLISM OF LIDOCAINE IN RATS [J].

KAWAI, R ;

FUJITA, S ;

SUZUKI, T .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1985, 74 (11) :1219-1224

[9] DISAPPEARANCE OF SEX DIFFERENCE IN RAT-LIVER DRUG-METABOLISM IN OLD-AGE [J].

KITAGAWA, H ;

FUJITA, S ;

SUZUKI, T ;

KITANI, K .

BIOCHEMICAL PHARMACOLOGY, 1985, 34 (04) :579-581

[10]

LELORIER J, 1977, J PHARMACOL EXP THER, V203, P507

← 1 2 →