VIGABATRIN IN INTRACTABLE CHILDHOOD EPILEPSY - A RETROSPECTIVE STUDY

被引：36

作者：

GIBBS, JM ^{[1
]}

APPLETON, RE ^{[1
]}

ROSENBLOOM, L ^{[1
]}

机构：

[1] ROYAL LIVERPOOL CHILDRENS HOSP, DEPT NEUROL, ALDER HEY, EATON RD, LIVERPOOL L12 2AP, ENGLAND

来源：

PEDIATRIC NEUROLOGY | 1992年 / 8卷 / 05期

关键词：

D O I：

10.1016/0887-8994(92)90086-E

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The effects of vigabatrin were studied over a 6-month period in 43 patients with intractable epilepsy. Children with complex partial seizures, with or without secondary generalization, responded best with more than one-half achieving a greater than 50% reduction; generalized tonic-clonic seizures also improved but there was no significant change in absence or myoclonic seizures. Four patients are seizure-free on monotherapy with vigabatrin. The drug was well tolerated with few side effects.

引用

页码：338 / 340

页数：3

共 15 条

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