SEX-CHROMOSOMES, RECOMBINATION, AND CHROMATIN CONFORMATION

被引:246
作者
MCKEE, BD
HANDEL, MA
机构
[1] Department of Zoology, University of Tennessee, Knoxville, 37996, TN
关键词
D O I
10.1007/BF00356023
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We review what is known about the transcriptional inactivation and condensation of heteromorphic sex chromosomes in contrast to the activation of homomorphic sex chromosomes during meiotic prephase in animals. We relate these cytological and transcriptional features to the recombination status of the sex chromosomes. We propose that sex chromosome condensation is a meiotic adaptation to prevent the initiation of potentially damaging recombination events in nonhomologous regions of the X and Y chromosome.
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页码:71 / 80
页数:10
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