ALPHAVIRUSES VECTORS FOR THE EXPRESSION OF HETEROLOGOUS GENES

被引：61

作者：

SCHLESINGER, S

机构：

[1] Department of Molecular Microbiology, Washington University School of Medicine, St Louis

来源：

TRENDS IN BIOTECHNOLOGY | 1993年 / 11卷 / 01期

关键词：

D O I：

10.1016/0167-7799(93)90070-P

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

DNA viruses and retroviruses are well established as vectors for the expression of heterologous genes, but there is increasing interest in the possibilities of using RNA viruses, which do not replicate through a DNA intermediate, for this purpose. This article summarizes some of the general properties of RNA viruses and concentrates on one class of RNA viruses - the alphaviruses - and their potential as expression vectors.

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页码：18 / 22

页数：5

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