ISOLATED VAGINAL CUFF RECURRENCE FOLLOWING THERAPY OF ENDOMETRIAL ADENOCARCINOMA

A group of 155 patients with Stage I and Stage II adenocarcinoma of the endometrium was treated with preoperative intrauterine, endocervical, and upper vaginal radiation, followed by total abdominal hysterectomy and bilateral salpingoophorectomy. Complications of the therapy were minimal. There were 3 recurrences involving the vagina (1.9 per cent) but none was an isolated vaginal cuff recurrence. On the basis of this experience, as well as that of others, the authors favor preoperative intracavitary radiation, designed to include the vaginal apex, in the therapy of endometrial carcinoma. © 1969.