A CORTICAL LECTIN FROM THE OOCYTES OF RUTILUS-RUTILUS STIMULATES MITOGENIC ACTIVITY AND RELEASE OF SOLUBLE FACTORS FROM HUMAN LYMPHOCYTE-CULTURES AND INHIBITS PROTEIN-SYNTHESIS IN A CELL-FREE SYSTEM

被引：9

作者：

LICASTRO, F ^{[1
]}

BARBIERI, L ^{[1
]}

KRAJHANZI, A ^{[1
]}

KOCOUREK, J ^{[1
]}

STRIPE, F ^{[1
]}

机构：

[1] CHARLES UNIV, DEPT BIOCHEM, CS-12840 PRAGUE, CZECHOSLOVAKIA

来源：

INTERNATIONAL JOURNAL OF BIOCHEMISTRY | 1991年 / 23卷 / 01期

关键词：

D O I：

10.1016/0020-711X(91)90015-F

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. A cortical granule lectin was isolated from vitellogenic oocytes of a bony fish, the roach Rutilus rutilus. 2. The lectin agglutinates human erythrocytes, is specific for L-rhamnose and is composed of different polypeptide subunits. 3. The lectin is the first lectin of animal origin that inhibits protein-synthesis by a rabbit reticulocyte lysate, and is also mitogenic for human lymphocytes.

引用

页码：101 / 105

页数：5

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