VISUALIZATION AND CHARACTERIZATION OF GASTRIC CONTRACTIONS USING A RADIONUCLIDE TECHNIQUE

被引:44
作者
URBAIN, JLC
VANCUTSEM, E
SIEGEL, JA
MAYEUR, S
VANDECRUYS, A
JANSSENS, J
DEROO, M
VANTRAPPEN, G
机构
[1] UNIV HOSP GASTHUISBERG, DIV GASTROENTEROL, B-3000 LOUVAIN, BELGIUM
[2] TEMPLE UNIV HOSP & MED SCH, NUCL MED SECT, PHILADELPHIA, PA 19140 USA
来源
AMERICAN JOURNAL OF PHYSIOLOGY | 1990年 / 259卷 / 06期
关键词
GASTRIC EMPTYING; CONTRACTION AMPLITUDE; PHASE IMAGE;
D O I
10.1152/ajpgi.1990.259.6.G1062
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
With the use of the radionuclide gastric-emptying test and a new data processing method, the contraction characteristics of the stomach were analyzed. After ingestion of a radiolabeled test meal, dynamic images of the stomach were acquired and analyzed to determine the frequency, amplitude, and rate of gastric contractions in healthy subjects. The frequency of antral contractions was found to be inversely related with food retention in the stomach; in contrast, the amplitude of the contractions decreased progressively during the course of gastric emptying. The peaks of both antral contraction and filling rate and the time of their occurrence remained constant throughout gastric emptying. The observed patterns of phase distribution and sequential phase changes of the food in the stomach confirmed noninvasively what was already known from invasive technique, i.e., that the proximal stomach does not undergo phasic contractions and that, in the distal stomach, smooth muscle contraction originates in midcorpus and propagates aborally to the pylorus. The scintigraphic test can be used to noninvasively and quantitatively characterize gastric motor function and to delineate the spatial sequence of gastric contractions. This technique can be applied to study the pathophysiology of gastric emptying in various motor disorders.
引用
收藏
页码:G1062 / G1067
页数:6
相关论文
共 20 条
[1]   ELECTROGASTROGRAPHY - CURRENT ASSESSMENT AND FUTURE PERSPECTIVES [J].
ABELL, TL ;
MALAGELADA, JR .
DIGESTIVE DISEASES AND SCIENCES, 1988, 33 (08) :982-992
[2]   GLUCAGON-EVOKED GASTRIC DYSRHYTHMIAS IN HUMANS SHOWN BY AN IMPROVED ELECTROGASTROGRAPHIC TECHNIQUE [J].
ABELL, TL ;
MALAGELADA, JR .
GASTROENTEROLOGY, 1985, 88 (06) :1932-1940
[3]  
BOTVINICK EH, 1987, CARDIAC NUCLEAR MED, P109
[4]  
Cannon W.B., 1898, AM J PHYSIOL, V1, P359, DOI 10.1152/ajplegacy.1898.1.3.359
[5]   MOTOR ACTION OF CANINE GASTRODUODENAL JUNCTION - A CINERADIOGRAPHIC PRESSURE AND ELECTRIC STUDY [J].
CARLSON, HC ;
CODE, CF ;
NELSON, RA .
AMERICAN JOURNAL OF DIGESTIVE DISEASES, 1966, 11 (02) :155-+
[6]   INTRACELLULAR ELECTRICAL-ACTIVITY OF CANINE AND HUMAN GASTRIC SMOOTH-MUSCLE [J].
ELSHARKAWY, TY ;
MORGAN, KG ;
SZURSZEWSKI, JH .
JOURNAL OF PHYSIOLOGY-LONDON, 1978, 279 (JUN) :291-307
[7]   MODULATION OF CANINE ANTRAL CIRCULAR SMOOTH-MUSCLE BY ACETYLCHOLINE, NORADRENALINE AND PENTAGASTRIN [J].
ELSHARKAWY, TY ;
SZURSZEWSKI, JH .
JOURNAL OF PHYSIOLOGY-LONDON, 1978, 279 (JUN) :309-320
[8]   MEASUREMENT OF RATE OF GASTRIC EMPTYING USING CHROMIUM-51 [J].
GRIFFITH, GH ;
OWEN, GM ;
KIRKMAN, S ;
SHIELDS, R .
LANCET, 1966, 1 (7449) :1244-&
[9]   REGULAR AND IRREGULAR CYCLES OF INTERDIGESTIVE CONTRACTIONS IN THE STOMACH [J].
ITOH, Z ;
AIZAWA, I ;
HONDA, R ;
TAKEUCHI, S ;
MORI, K .
AMERICAN JOURNAL OF PHYSIOLOGY, 1980, 238 (02) :G85-G90
[10]   CHARACTERISTIC MOTOR-ACTIVITY OF GASTROINTESTINAL-TRACT IN FASTED CONSCIOUS DOGS MEASURED BY IMPLANTED FORCE TRANSDUCERS [J].
ITOH, Z ;
TAKEUCHI, S ;
AIZAWA, I ;
TAKAYANAGI, R .
AMERICAN JOURNAL OF DIGESTIVE DISEASES, 1978, 23 (03) :229-238