A NEW STRATEGY FOR DIRECTED PROTEIN CLEAVAGE

被引:79
作者
CUENOUD, B [1 ]
TARASOW, TM [1 ]
SCHEPARTZ, A [1 ]
机构
[1] YALE UNIV,DEPT CHEM,NEW HAVEN,CT 06511
基金
美国国家科学基金会;
关键词
D O I
10.1016/S0040-4039(00)91569-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Attachment of a Ni(II)-glyglyhis chelate to trifluoperazine results in a molecule capable of cleaving calmodulin at a single locus upon activation with a peracid.
引用
收藏
页码:895 / 898
页数:4
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