ALCOHOLISM AND THE D2 RECEPTOR GENE

被引:72
作者
COOK, BL
WANG, ZW
CROWE, RR
HAUSER, R
FREIMER, M
机构
[1] UNIV IOWA, COLL MED, IOWA CITY, IA 52242 USA
[2] UNIV IOWA HOSP & CLIN, IOWA CITY, IA 52242 USA
关键词
ALCOHOLISM; GENETICS; DOPAMINE;
D O I
10.1111/j.1530-0277.1992.tb00683.x
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
The allelic association of the human dopamine D2 receptor gene and alcoholism was evaluated in 20 male alcoholics and 20 controls (sex, race, and geographic place of birth matched). This study further examines the issue of alcoholism severity and A1 allele frequency. No difference in A1 allele frequency was observed between these two groups. Similarly, no relationship between alcoholism severity and A1 frequency within the alcoholics was demonstrated.
引用
收藏
页码:806 / 809
页数:4
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