PLASTICITY OF CENTRAL MOTOR PATHWAYS IN CHILDREN WITH HEMIPLEGIC CEREBRAL-PALSY

被引：186

作者：

FARMER, SF ^{[1
]}

HARRISON, LM ^{[1
]}

INGRAM, DA ^{[1
]}

STEPHENS, JA ^{[1
]}

机构：

[1] ROYAL LONDON HOSP,DEPT CLIN NEUROPHYSIOL,LONDON,ENGLAND

来源：

NEUROLOGY | 1991年 / 41卷 / 09期

基金：

英国惠康基金;

关键词：

D O I：

10.1212/WNL.41.9.1505

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To obtain neurophysiologic evidence for a reorganization of central motor pathways in children who had suffered a cerebral lesion at birth, we performed cross-correlation analyses of multiunit EMG recordings obtained from children with hemiplegic cerebral palsy and marked mirror movements. We found that the motoneuron pools of homologous left and right hand muscles received common synaptic input from abnormally branched presynaptic axons. The results of electromagnetic brain stimulation, cutaneomuscular, and tendon reflex testing suggested that these common inputs are provided by abnormally branched corticospinal tract fibers whose origin is the undamaged motor cortex.

引用

页码：1505 / 1510

页数：6

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