SERUM FERRITIN IN NEWLY DIAGNOSED AND POORLY CONTROLLED DIABETES-MELLITUS

被引：20

作者：

DINNEEN, SF

OMAHONY, MS

OBRIEN, T

CRONIN, CC

MURRAY, DM

OSULLIVAN, DJ

机构：

[1] Department of Medicine, Cork Regional Hospital, Cork

[2] Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, 55905

来源：

IRISH JOURNAL OF MEDICAL SCIENCE | 1992年 / 161卷 / 11期

关键词：

D O I：

10.1007/BF02983771

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Serum ferritin was measured in 50 patients at diagnosis of diabetes mellitus (DM) a patients with established DM and poor metabolic control. Twenty-two patients had hyperferritinemia at diagnosis. Four patients had a recognised cause for their hyperferritinemia. In the remaining 18 patients ferritin levels decreased from a mean of 506 +/- 3.6 (SE) ug/l at diagnosis to 254 +/- 29.2 ug/l seven months later (p<0.001). Metabolic control improved significantly over the same time. All 20 patients with established DM and poor metabolic control had normal ferritin levels. When compared with the newly diagnosed hyperferritinemic patients no difference was found in levels of glycosylated haemoglobin, but ferritin values differed significantly between the two groups (p<0.001). These results indicate that transient hyperferritinemia is a feature of newly diagnosed DM but not of established DM with poor control. If used to screen diabetic patients for haemochromatosis, serum ferritin should be measured in established DM rather than at diagnosis.

引用

页码：636 / 638

页数：3

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