CI-867, A NEW BROAD-SPECTRUM SEMI-SYNTHETIC PENICILLIN

被引：10

作者：

KALTENBRONN, JS

HASKELL, TH

DOUB, L

KNOBLE, J

DEJOHN, D

KROLLS, U

JENESEL, N

HUANG, GG

HEIFETZ, CL

FISHER, MW

机构：

[1] Warner-Lambert/Parke-Davis Pharmaceutical Research Division, Ann Arbor, Michigan

来源：

JOURNAL OF ANTIBIOTICS | 1979年 / 32卷 / 06期

关键词：

D O I：

10.7164/antibiotics.32.621

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The synthesis and antimicrobial activity of a new semisynthetic penicillin are described. Both in vitro and in vivo, the compound shows promising antibacterial activity when compared with piperacillin and ticarcillin. High activity is shown against Pseudomonas and other Gram-negative bacteria. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：621 / 625

页数：5

共 6 条

[1] USE OF ESTERS OF N-HYDROXYSUCCINIMIDE IN PEPTIDE SYNTHESIS
ANDERSON, GW
CALLAHAN, FM
ZIMMERMAN, JE
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (09) : 1839 - +
[2] BUTIROSIN COMPARED WITH GENTAMICIN INVITRO AND INVIVO
HEIFETZ, CL
CHODUBSKI, JA
PEARSON, IA
SILVERMAN, CA
FISHER, MW
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1974, 6 (02) : 124 - 135
[3] KALTENBRONN JS, 1978, Patent No. 4101661
[4] INVITRO AND INVIVO ACTIVITY OF PIPERACILLIN, A NEW BROAD-SPECTRUM SEMI-SYNTHETIC PENICILLIN
KUCK, NA
REDIN, GS
[J]. JOURNAL OF ANTIBIOTICS, 1978, 31 (11) : 1175 - 1182
[5] CONDENSATIONS OF UNSYMMETRICAL KETONES .1. CONDENSATIONS WITH ETHYL FORMATE
MARIELLA, RP
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1947, 69 (11) : 2670 - 2672
[6] INVITRO AND INVIVO ANTIBACTERIAL ACTIVITY OF T-1220, A NEW SEMISYNTHETIC PENICILLIN
UEO, K
FUKUOKA, Y
HAYASHI, T
YASUDA, T
TAKI, H
TAI, M
WATANABE, Y
SAIKAWA, I
MITSUHASHI, S
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1977, 12 (04) : 455 - 460

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