IDENTIFICATION OF BILE-ACID METHYL-ESTERS BY GAS-CHROMATOGRAPHY METHANE CHEMICAL IONIZATION MASS-SPECTROMETRY

被引：11

作者：

MUSCHIK, GM

WRIGHT, LH

SCHROER, JA

机构：

[1] NCI Frederick Cancer Research Center, Frederick, Maryland

[2] Environmental Protection Agency, North Carolina, 27711, Research Triangle Park

[3] Bruker Instruments, Inc., Billerica, Massachusetts, 01821, Menning Park

来源：

BIOMEDICAL MASS SPECTROMETRY | 1979年 / 6卷 / 06期

关键词：

D O I：

10.1002/bms.1200060608

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Methane chemical ionization mass spectrometric data and gas chromatography retention parameters are reported for 31 bile acid methyl esters. The group includes both saturated and unsaturated compounds with up to three keto or hydroxyl groups. Major ions include the quasimolecular ions and fragments resulting from the loss of neutral species such as methanol, water and methane. The combination of gas‐liquid chromatography retention and mass spectral data is sufficient for an unequivocal distinction among all the bile acids studied. Application of this data to the identification of bile acid metabolites is cited. Copyright © 1979 Heyden & Son Ltd

引用

页码：266 / 270

页数：5

共 14 条

[1]

BERGSTROM S, 1961, SVENSK KEM TIDSKR, V73, P566

[2] IMPROVED METHOD FOR ISOLATION, QUANTITATION, AND IDENTIFICATION OF BILE-ACIDS IN RAT FECES [J].