RELATIONSHIP BETWEEN METRONIDAZOLE METABOLISM AND BACTERICIDAL ACTIVITY

被引：56

作者：

CHRYSTAL, EJT ^{[1
]}

KOCH, RL ^{[1
]}

MCLAFFERTY, MA ^{[1
]}

GOLDMAN, P ^{[1
]}

机构：

[1] HARVARD UNIV,BETH ISRAEL HOSP,SCH MED,DEPT PHARMACOL,DIV CLIN PHARMACOL,BOSTON,MA 02215

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1980年 / 18卷 / 04期

关键词：

D O I：

10.1128/AAC.18.4.566

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

引用

页码：566 / 573

页数：8

共 17 条

[1] MAMMALIAN-CELL TOXICITY OF NITRO-COMPOUNDS - DEPENDENCE UPON REDUCTION POTENTIAL
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[2] ELECTRON-AFFINIC SENSITIZATION .7. CORRELATION BETWEEN STRUCTURES ONE-ELECTRON REDUCTION POTENTIALS, AND EFFICIENCIES OF NITROIMIDAZOLES AS HYPOXIC CELL RADIOSENSITIZERS
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SMITHEN, CE
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[J]. RADIATION RESEARCH, 1976, 67 (01) : 9 - 20
[3] BAHNEMANN D, 1978, BRIT J CANCER, V37, P16
[4] SCREENING FOR MUTAGENICITY OF NITRO-GROUP CONTAINING HYPOXIC CELL RADIOSENSITIZERS USING SALMONELLA-TYPHIMURIUM STRAINS-TA100 AND STRAINS-TA98
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RAUTH, AM
[J]. MUTATION RESEARCH, 1978, 58 (01): : 1 - 10
[5] SELECTIVE TOXICITY OF ANTIMICROBIAL NITROHETEROCYCLIC DRUGS
EDWARDS, DI
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CARNE, H
[J]. JOURNAL OF GENERAL MICROBIOLOGY, 1973, 76 (MAY): : 135 - 145
[6] GILLETTE JR, 1971, HDB EXPTL PHARMACO 2, V28, P349
[7] MODE OF ACTION OF METRONIDAZOLE IN TRICHOMONAS-VAGINALIS AND OTHER MICROORGANISMS
INGS, RMJ
MCFADZEAN, JA
ORMEROD, WE
[J]. BIOCHEMICAL PHARMACOLOGY, 1974, 23 (09) : 1421 - 1429
[8] INTERACTION OF REDUCED METRONIDAZOLE WITH DNA
KNIGHT, RC
SKOLIMOWSKI, IM
EDWARDS, DI
[J]. BIOCHEMICAL PHARMACOLOGY, 1978, 27 (17) : 2089 - 2093
[9] KOCH RL, 1979, J PHARMACOL EXP THER, V208, P406
[10] ACETAMIDE - METABOLITE OF METRONIDAZOLE FORMED BY THE INTESTINAL FLORA
KOCH, RL
CHRYSTAL, EJT
BEAULIEU, BB
GOLDMAN, P
[J]. BIOCHEMICAL PHARMACOLOGY, 1979, 28 (24) : 3611 - 3615

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