VISUAL DYSFUNCTION IN PATIENTS WITH MITOCHONDRIAL MYOPATHIES .1. ELECTROPHYSIOLOGIC IMPAIRMENTS

被引：5

作者：

AMBROSIO, G

DEMARCO, R

LOFFREDO, L

MAGLI, A

机构：

[1] Istituto di Oftalmologia, II Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli, Napoli, 80131

来源：

DOCUMENTA OPHTHALMOLOGICA | 1995年 / 89卷 / 03期

关键词：

PEO; PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA;

D O I：

10.1007/BF01203374

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Seventeen patients with biopsy-confirmed mitochondrial progressive external ophthalmoplegia underwent electroretinography and visual evoked potential testing to checkerboard-reversal stimuli to investigate subclinical visual dysfunction. Seven patients (41%) had impaired Snellen visual acuity that ws never less than 0.6. Thirteen patients (76%) showed electroretinographic and/or visual evoked potential alterations, whereas six (35%) showed impairment on both tests. Two patients showed delayed VEP P100 latency without fundus, electroretinographic or visual acuity anomalies. Visual dysfunctions were not related to age at onset and course of the disease.

引用

页码：211 / 218

页数：8

共 25 条

[1]

Bastiaensen L A, 1989, Bull Soc Belge Ophtalmol, V237, P381

[2]

BASTIAENSEN LAK, 1978, ACTA OPHTHALMOL, P5

[3] ERG AND VECP IN CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA (CPEO) [J].

BERDJIS, H ;

HEIDER, W ;

DEMISCH, K .

DOCUMENTA OPHTHALMOLOGICA, 1985, 60 (04) :427-434

[4] PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA ASSOCIATED WITH RETINAL-PIGMENT EPITHELIOPATHY [J].

DANIELE, S ;

CIANCHETTI, C ;

CAO, A .

AMERICAN JOURNAL OF OPHTHALMOLOGY, 1975, 80 (04) :585-590

[5]

DANIELE S, 1988, B OCUL, V67, P413

[6] OPHTHALMOPLEGIA PLUS - NEURODEGENERATIVE DISORDERS ASSOCIATED WITH PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA [J].

DRACHMAN, DA .

ARCHIVES OF NEUROLOGY, 1968, 18 (06) :654-+

[7] CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA - A CORRELATIVE STUDY OF MITOCHONDRIAL-DNA DELETIONS AND THEIR PHENOTYPIC-EXPRESSION IN MUSCLE BIOPSIES [J].

GOTO, Y ;

KOGA, Y ;

HORAI, S ;

NONAKA, I .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 1990, 100 (1-2) :63-69

[8] MITOCHONDRIAL MYOPATHY OR MITOCHONDRIAL DISEASE - EEG, ERG, VEP STUDIES IN 13 CHILDREN [J].

HARDEN, A ;

PAMPIGLIONE, G ;

BATTAGLIA, A .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1982, 45 (07) :627-632

[9] DELETIONS OF MUSCLE MITOCHONDRIAL-DNA IN PATIENTS WITH MITOCHONDRIAL MYOPATHIES [J].

HOLT, IJ ;

HARDING, AE ;

MORGANHUGHES, JA .

NATURE, 1988, 331 (6158) :717-719

[10] A PARTIAL DEFICIENCY OF CYTOCHROME-C OXIDASE IN CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA [J].

JOHNSON, MA ;

TURNBULL, DM ;

DICK, DJ ;

SHERRATT, HSA .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 1983, 60 (01) :31-53

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