PI-ALLYL PALLADIUM RING-CLOSURE STRATEGY FOR THE SYNTHESIS OF A 1-BETA-METHYLCARBAPENEM INTERMEDIATE

被引：21

作者：

ROLAND, S

DURAND, JO

SAVIGNAC, M

GENET, JP

JUNG, F

机构：

[1] ECOLE NATL SUPER CHIM,SYNTH ORGAN LAB,CNRS,URA 1381,F-75231 PARIS,FRANCE

[2] ZENECA PHARMA,CTR RECH,F-51064 REIMS,FRANCE

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 17期

关键词：

PALLADIUM CATALYST; CYCLIZATION; 1-METHYLENECARBAPENEM;

D O I：

10.1016/0040-4039(95)00448-L

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new ring closure by pi-allyl palladium methodology is utilized in the synthesis of a 1-beta-methyl carbapenem intermediate from 2-acetoxy azetidinone in six steps (40% yield).

引用

页码：3007 / 3010

页数：4

共 18 条

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