COMPARISON OF THERAPEUTIC ROUTES IN EXPERIMENTAL PSEUDOMONAS KERATITIS

被引：33

作者：

DAVIS, SD

SARFF, LD

HYNDIUK, RA

机构：

[1] MED COLL WISCONSIN, MILWAUKEE CHILDRENS HOSP, DEPT PEDIAT, MILWAUKEE, WI 53233 USA

[2] MILWAUKEE CTY MED COMPLEX, CORNEA EXTERNAL EYE DIS UNIT, MILWAUKEE, WI USA

[3] MED COLL WISCONSIN, MILWAUKEE CHILDRENS HOSP, DEPT OPHTHALMOL, MILWAUKEE, WI 53233 USA

[4] MILWAUKEE CTY MED COMPLEX, INST EYE, MILWAUKEE, WI USA

来源：

AMERICAN JOURNAL OF OPHTHALMOLOGY | 1979年 / 87卷 / 05期

关键词：

D O I：

10.1016/0002-9394(79)90309-X

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The efficacy of tobramycin administered by topical, i.m. and subconjunctival routes in guinea pigs and rabbits with experimental Pseudomonas keratitis was determined. The topical route of administration was consistently more effective than either subconjunctival or i.m. routes. Subconjunctival injection of antibiotic did not enhance the effectiveness of topical therapy in either guinea pigs or rabbits. Tobramycin i.m. was more effective than saline in guinea pigs with keratitis but not in rabbits with keratitis.

引用

页码：710 / 716

页数：7

共 10 条

[1]

BAUM J L, 1973, International Ophthalmology Clinics, V13, P31, DOI 10.1097/00004397-197301340-00004

[2] CONCENTRATION OF GENTAMICIN IN EXPERIMENTAL CORNEAL ULCERS - TOPICAL VS SUBCONJUNCTIVAL THERAPY [J].