FAST-ATOM-BOMBARDMENT MASS-SPECTROMETRY IN THE STUDY OF DOPAMINE MELANOGENESIS INTERMEDIATES

被引：14

作者：

ALLEGRI, G ^{[1
]}

ARBAN, R ^{[1
]}

COSTA, C ^{[1
]}

BIASIOLO, M ^{[1
]}

CURCURUTO, O ^{[1
]}

POZZAN, A ^{[1
]}

TRALDI, P ^{[1
]}

机构：

[1] CNR,SERV SPETTROMETRIA MASSA,I-35100 PADUA,ITALY

来源：

PIGMENT CELL RESEARCH | 1990年 / 3卷 / 04期

关键词：

MELANOGENESIS INTERMEDIATES; DOPAMINE-MELANIN; FAST ATOM BOMBARDMENT;

D O I：

10.1111/j.1600-0749.1990.tb00287.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Fast atom bombardment was applied to the study of the intermediates of the reaction dopamine-tyrosinase after treatment with diazomethane. The identification of trimethoxylindoline, dopamine-o-quinone and dimethoxyindole was easily achieved by this ionization method, together with accurate mass measurements and collision experiments. The structures of these compounds are in agreement with those already hypothesized in studies on melanogenesis.

引用

页码：181 / 186

页数：6

共 17 条

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