BENZOTRIAZOLE-ASSISTED SYNTHESIS OF ENAMINES

被引：27

作者：

KATRITZKY, AR

LONG, QH

LUE, P

JOZWIAK, A

机构：

[1] Department of Chemistry University of Florida, Gainesville

来源：

TETRAHEDRON | 1990年 / 46卷 / 24期

关键词：

D O I：

10.1016/S0040-4020(01)81471-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new, facile preparation of enamines was achieved via a two-step sequence: (i) the ready formation of an N-(α-aminoalkyl)benzotriazole derivative from equimolar amounts of benzotriazole, an aldehyde, and a secondary amine, (ii) the elimination of benzotriazole from the derivative by sodium hydride in tetrahydrofuran (THF). The method provides enamines in good overall yields based on the quantity of amine used. © 1990.

引用

页码：8153 / 8160

页数：8

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