A STRAIGHTFORWARD ROUTE TO FUNCTIONALIZED INTERMEDIATES CONTAINING THE CD SUBSTRUCTURE OF TAXOL

被引:56
作者
MAGEE, TV
BORNMANN, WG
ISAACS, RCA
DANISHEFSKY, SJ
机构
[1] Laboratory of Bio-Organic Chemistry, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York 10021
关键词
D O I
10.1021/jo00038a008
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The Wieland-Miescher ketone lends itself to conversion, in a few steps, to intermediates which could well be useful for a synthesis of taxol (1) and analogs thereof.
引用
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页码:3274 / 3276
页数:3
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