THE EFFECT OF REMOTE OXYGENS ON THE RING-OPENING REACTIONS OF OXABICYCLIC COMPOUNDS WITH ORGANOLITHIUM REAGENTS - SYNTHESIS OF THE C21-C27 SEGMENT OF RIFAMYCIN-S

被引：35

作者：

LAUTENS, M

BELTER, RK

机构：

[1] Department of Chemistry University of Toronto, Toronto

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 19期

关键词：

D O I：

10.1016/S0040-4039(00)79040-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reactivity of several related oxabicyclo[3.2.1]octenes toward ring-opening was found to depend on the stereochemistry of a remote hydroxyl group. It was also found that attenuation of the reactivity occurred upon protection of the remote alcohol.

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页码：2617 / 2620

页数：4

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